Normally, one client is associated to one currency, but it can happen that a client uses two different currencies.

In LSP.expert, you can only define one currency for a client, but there is a workaround to handle the "multi-currency clients". 

You should simply create two different clients for the same client: one client that would be called "Client XYZ - EUR" for example, and another client that would be called "Client XYZ - USD". 

When creating the job, you should then simply select the right "version" of the client depending on the currency you have to use for this job in particular.

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